Best Oral Pain Treatments (Dec. 2024) - Rated by CherryPicks' Experts

At a Glance: Our Top Picks

Top 1

DenTek Instant Oral Pain Relief Maximum Strength Kit for Toothaches | 50 Count

9.8
CPR Score
Top 2

Orajel 4X for Toothache & Gum Pain: Severe Cream Tube 0.33oz- From Oral Pain ...

9.7
CPR Score
Top 3

Anbesol Maximum Strength Oral Pain Relief Gel, Instant Pain Relief For Tootha...

9.7
CPR Score
Tips


Our Oral Pain Treatments Ranking is based on our detailed analysis of 610 Oral Pain Treatments and over 196,273 customer reviews. We have compiled the top 28 Best Oral Pain Treatments you might be interested in and ratings based on product features.

* CherryPicks.Reviews is reader-supported, Our editor review, and recommend the best products based on extensive data analysis, if you click on the product links, we may earn a commission through qualifying products purchased.

The Best Oral Pain Treatments Rated by CherryPicks

Market Overview
Oral Pain Treatments Reviewed
  • Reviews Analyzed: 196,273 Items
  • CPR Avg. Rating: 8.5 / 10
28 Products Evaluated
  • Highest Price: $114.45
  • Lowest Price: $4.17
  • Avg. Price: $12.66
Price Disclaimer

Top 28 Oral Pain Treatments on Amazon (Verified You can Buy)

DenTek Instant Oral Pain Relief Maximum Strength Kit for Toothaches | 50 Count

DenTek
00352
3.95 x 1.19 x 4.03 Inches
0.0 Pounds

Ratings for DenTek (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
Wiki Deals 53

Features

DenTek Instant Pain Relief, Advanced Kit gives instant and precise relief from oral pain and toothaches
Ergonomic handle to reach any area of the mouth gives simple, no-fingers no-mess, relief
Show More

Orajel 4X for Toothache & Gum Pain: Severe Cream Tube 0.33oz- From Oral Pain Relief Brand

Orajel
Orajel, orajel, toothache
4.375 x 1.0 x 3.688 Inches
0.021 Pounds

Ratings for Orajel (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
Surprise Dealz -

Features

INSTANT PAIN RELIEF: Instant pain relief with Orajel’s unique 4X clinical strength formula to help relieve pain of the tooth and gums
4X ACTIVE INGREDIENTS: With 4 active ingredients, Orajel Cream provides fast acting and maximum strength relief when you need it most
Show More

Anbesol Maximum Strength Oral Pain Relief Gel, Instant Pain Relief For Toothache Pain, Canker Sores, Sore Gums, Mouth Sores, Denture Pain, and Aligner Pain, ADA Accepted, 0.33 oz (packaging may vary)

Anbesol
305730225670
0.0206 Pounds

Ratings for Anbesol (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

INSTANT PAIN RELIEF: Instant oral pain relief for mouth and gum irritation due to toothaches, canker sores, sore gums, denture pain, and minor dental procedures. Use with dentures to relieve discomfort.
MAXIMUM STRENGTH: Instant relief that takes you from ouch to ahhh! So, oral pain doesn’t hold you back. Formulated with 20% Benzocaine to offer maximum strength pain relief and instantly soothe mouth pain and dental irritation
Show More

Oral-B Mouth Sore Mouthwash Special Care Oral Rinse, 475 mL (16 fl oz)

Oral-B
B07ZJZWJ7R
2.44 x 2.44 x 8.5 Inches
1.0 Pounds

Ratings for Oral-B (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

Oral-B special care rinse collection is crafted to meet your unique oral care needs
Specially formulated for Mouth Sores, including: Canker Sores, Cheek Bites, Braces & Denture Irritations, Oral & Gum Irritations
Show More

Benzodent Dental Pain Relieving Cream for Dentures and Braces, Topical Anesthetic, 0.25 Ounce Tube

Benzodent
10041167005320
3.75 x 1.06 x 3.13 Inches
0.0154 Pounds

Ratings for Benzodent (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

FOR DENTAL PAIN: Benzodent provides temporary relief of pain for oral discomfort caused by dentures, braces or sores, with the maximum amount of benzocaine allowed in an over the counter oral product.
LONG LASTING RELIEF: Benzodent is a thick topical cream that provides pain relief with the strength of benzocaine. The unique formula cushions & adheres to gums for pain relief that lasts for hours.
Show More

Red Cross Toothache Medication Drops

Red Cross
PPAX1236955
0.98 x 3.62 x 4.24 Inches
0.2 Pounds

Ratings for Red Cross (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
epharmastore 3,744
Bleam 677
HerbsPro 7,236
Celerity Arbitrators -

Features

Product of Red Cross

Orajel Maximum Strength Nighttime Toothache Pain Relief Cream - 0.25 Oz

Orajel
31854
3.75 x 3.25 x 1.0 Inches
0.0156 Pounds

Ratings for Orajel (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Pharmapacks 435
LY Berditchev Co. 56
The Perfect Deals 1,074
RGM GROUP 242
Aidleyco 2,964
A & H Supply 548
IDMACommerce 4,607

Features

Powerful nighttime relief: Orajel Maximum Strength Nighttime Toothache Pain Relief Cream provides maximum strength relief to alleviate toothache pain.
Targeted application: The cream is conveniently applied directly to the affected tooth and gum area, delivering fast-acting relief precisely where you need it most.
Show More

S.t.37 Mouth Pain Relief Solution - 16 Oz

S&T INC.
1.05 Pounds

Ratings for S&T INC. (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
VerSure 26
Mr. Medical 82
Pharmapacks 435
Lancaster South -
SportingDoc 88

Orajel 3X for Mouth Sores: Maximum Strength Gel Tube 0.42oz- from #1 Oral Pain Relief Brand- for Instant Pain Relief

Orajel
10310310000285
4.375 x 1.0 x 3.688 Inches
0.026 Pounds

Ratings for Orajel (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
Titan Earth Designs -

Features

INSTANT PAIN RELIEF: Orajel Mouth Sore Gel contains 20% Benzocaine to relieve pain from canker sores, mouth sores, cold sores and other mouth irritations
SOOTHING RELIEF: Maximum strength gel uses menthol to soothe irritated and sore gums quickly, where you need it most
Show More

GUM - 1770R Rincinol P.R.N. Alcohol-Free Mouth Sore Rinse, 4 Ounce Bottle

GUM
1770R
6.25 x 2.25 x 2.24 Inches
0.25 pounds

Ratings for GUM (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
SKYLINE HOMES -

Features

This oral rinse provides gentle protection, healing and pain relief from mouth sores. Its aloe vera based formula helps promote the healing of aphthous ulcers, irritations from orthodontic appliances and removable dentures, and minor cuts and abrasions
This specially formulated rinse creates a micro-thin, invisible, bio-adhesive protective barrier which shields sensitive nerve-endings from irritants such as food, drinks, braces, or dentures. Provides fast and effective pain relief for up to 6 hours
Show More

Orajel 3X for Toothache & Gum Pain: Maximum Gel Tube 0.42oz - From #1 Oral Pain Relief Brand - Orajel for Instant Pain Relief

Orajel
Orajel Maximum Strength Gel
1.0 x 4.375 x 3.75 Inches
0.04 Pounds

Ratings for Orajel (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
Vitabox 687
Cary's Store, LLC 6,966
ISKOLIVE 12 INC 1,704
K & B Corner LLC -
Playthings Aplenty LLC -

Features

INSTANT PAIN RELIEF: Instant pain relief with Orajel’s maximum strength formula to help relieve pain of the tooth and gums with 20% benzocaine
KILLS HARMFUL BACTERIA: Unique formula is designed to help kill harmful bacteria in the mouth, and can help to prevent infections
Show More

DenTek Adult Instant Tooth Pain Relief Kit With 50 Applicators (Pack of 2)

DenTek
4.0 x 1.0 x 4.0 Inches
0.28 Pounds

Ratings for DenTek (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Pharmapacks 435
LET'S BUY 991
GO SHOP INC -

Features

DenTek Instant Pain Relief, Advanced Kit gives instant and precise relief from oral pain and toothaches
Ergonomic handle to reach any area of the mouth gives simple, no-fingers no-mess, relief
Show More

DenTek Canker Relief Sore Patch Relieves Canker Pain, 6 Count (Pack of 1)

DenTek

Ratings for DenTek (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
Primegoods2 -
Myreliablemart 4,257

Features

DenTek Canker Relief Advanced Canker Sore Patches help provide relief from canker sore pain and help protect from irritants while promoting healing
Clinically tested to reduce canker sore pain and help relieve the pain from small oral wounds and irritation from braces and oral ulcers
Show More

Orajel 4X for Toothache & Gum Pain Severe Gel Tube, No Color, 0.25 Ounce

Orajel
310310325039
1.0 x 3.188 x 3.75 Inches
0.016 Pounds

Ratings for Orajel (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
Mr. Medical 82
LY Berditchev Co. 56
Wiki Deals 53
MurMur Center 6,875
ISKOLIVE 12 INC 1,704
I Buy Direct 999

Features

Clinical Strength Pain Relief
Proven to Kill Harmful Bacteria
Show More
Top 15

ORAL ANALGESIC GEL 0.42 OZ

IODENT

Ratings for IODENT (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
AWEGOO 4,967
Thee Mall 3,310
Quality-Boutique -
The Best For Less 8,537
JAC COLLECTION -

Features

Iodent Compare to the active ingredient of ORAJEL
ORAJEL
Show More
Top 16

Orajel Toothache Rinse, Analgesic Astringent, Soothing Mint, 16 fl oz

Orajel
464767
3.82 x 2.5 x 8.125 Inches
1.125 Pounds

Ratings for Orajel (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
Pharmapacks 435
HerbsPro 7,236
VOI Products 6,829

Features

DOUBLE MEDICATED: First and only double medicated toothache rinse for the temporary relief of pain due to toothaches and minor irritation of the mouth and gums, or occasional minor irritation, pain, sore mouth and sore throat.
ALL OVER ORAL PAIN RELIEF: Orajel Toothache Rinse contains an oral pain reliever to help to provide you with all over oral pain relief.
Show More

Blistex Kanka Mouth Pain Liquid, Professional Strength , .33 Fluid Ounces

Kanka
41500
0.8 x 3.0 x 5.0 Inches

Ratings for Kanka (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Royal Meds 115
Lava Vitality 733
SellLogic 6,258

Features

The Complete Solution for canker sores and other sores in the mouth
Maximum-strength pain medication (benzocaine) for fast temporary pain relief
Show More

Plackers Grind No More Night Guard, Nighttime Protection for Teeth, BPA Free, Sleep Well, Ready to Wear, Disposable, One Size Fits All, 16 Count

Plackers
SA204JR
7.28 x 4.65 x 6.77 inches
0.0019 Pounds
  • Contributor: Plackers

Ratings for Plackers (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

Includes: 16 disposable dental guards with up to 48 uses
Grind No More: Featuring patented clench and grind absorbing bite plates to stop you from grinding your teeth during the night and to increase peaceful sleep
Show More

ASRL Mouth Guard for Clenching Teeth at Night, Night Guards for Teeth Grinding (4 Pack, 2 Sizes)

ASRL

Ratings for ASRL (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Wangcare -
LUCKY CLOVER STORE -
Angel Nealtly -

Features

Health Professional Mouth Guard - ASRL (Advanced Sleep Research Laboratory) aims at developing advanced techniques to help you get a good night's sleep.
Comfortable & Moldable - Our mouth guards for grinding teeth are made of ethylene vinyl acetate which can easily be molded in hot water and thus adjusted to your bite. It is the best choice to protect your teeth from the wear and damage caused by grinding.
Show More

Colgate Whitening Toothpaste for Sensitive Teeth, Enamel Repair and Cavity Protection, Fresh Mint Gel, 6 Oz (Pack of 3)

Colgate
10035000453386
7.78 x 1.687 x 6.0 Inches
1.1 Pounds

Ratings for Colgate (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

Specialty Whitening Toothpaste for Sensitive Teeth
Sensitive Teeth Toothpaste, Provides 24/7 Sensitivity Protection (with twice-daily brushing)
Show More

DenTek Ultimate Guard for Nighttime Teeth Grinding

DenTek
B07M9Z6ZMN
7.4 x 7.2 x 3.8 Inches

Ratings for DenTek (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
Stam Sales 731
Small shop BIG savings -
CVG SURPLUS -

Features

DenTek Ultimate Guard fits the front and back teeth and comes with a SmartFit Tray to help provide a dentist-quality fit like a full coverage guard
BPA free, made in the USA, and quickly customizable in 3 easy steps (read all instructions and watch the full video before fitting)
Show More

DenTek Comfort-Fit Dental Guards for Nighttime Teeth Grinding, 2 Count

DenTek
00015101203I2
6.0 x 4.0 x 5.0 inches
0.5 Pounds
  • Contributor: DenTek

Ratings for DenTek (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
ZebraTech -

Features

DenTek Comfort-Fit Dental Guards are ready-to-wear with a slim, secure fit on the lower teeth to provide the same level of protection as a full coverage dental guard
BPA and latex free, and ready-to-use straight out of the box – no boiling required
Show More

Neomen Mouth Guards for Grinding Teeth, bite guard for teeth clenching nighttime, bruxism mouth guard bite dental guards nightguard for sleep teeth grinding, Pack of 4

NEOMEN

Ratings for NEOMEN (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
srfegvf -
Haixian illum -
SSuperSound -
Protech Dental US -
brighfuture -

Features

SOFT AND COMFORTABLE: Absolutely the best soft braces money can buy. Our mouthguards for grinding of teeth are super soft and customizable without being tight and bulky.
PERFECTLY CUSTOMIZED: Neomen Mouthguards are made from moldable material and can be customized to fit any mouth shape. Our night guard set includes 4 mouth guards; 2 premium designs in different sizes. Whether you are a child, teen or adult, our mouthguard is just fit for you.
Show More

Gly-Oxide Alcohol-Free Antiseptic Mouth Sore Rinse, 2 oz

Gly-Oxide
SG_B00ANL55Y2_US
1.63 x 1.75 x 4.88 Inches
0.125 Pounds

Ratings for Gly-Oxide (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
ZP450 LLC -

Features

3 in 1 action cleanses minor mouth & gum irritation
Soothes canker sores & braces irritation
Show More

Neosporin Lip Health Overnight Renewal Therapy White Petrolatum Lip Protectant, Lip Moisturizer to Nourish & Repair Dry Lips, Helps Relieve, Prevent & Protect Chapped Lips, 0.27 oz, 2 Pack

Neosporin
00312547042581

Ratings for Neosporin (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

Twin pack containing two 0.27-ounce tubs of Neosporin Lip Health Overnight Renewal Therapy Lip Protectant with white petrolatum to help hydrate and nourish your lips, the most fragile skin on your body
This hydrating overnight lip treatment reduces the signs and symptoms of dryness, such as scaling, cracking and chapping, and is clinically shown to restore visibly healthier lips in just three days
Show More

DenTek Mouth Guard for Nighttime Teeth Grinding, Professional-Fit Dental Guard, 1 Count

DenTek
100277
3.75 x 2.0 x 6.13 Inches
0.08 Pounds
  • Contributor: DenTek

Ratings for DenTek (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
Lightning Online 8,254
Gaudum -

Features

DenTek Professional-Fit Dental Guard fits the front and back teeth and offers custom-fit protection similar to a professionally made mouth guard – for a fraction of the cost
BPA free, and quickly customizable in 3 easy steps (read all instructions and watch the full video before fitting)
Show More

Benzodent Dental Pain Relieving Cream for Dentures and Braces, Topical Anesthetic, 1 Ounce Tube

Benzodent
10041167005344
4.75 x 1.06 x 1.13 Inches
0.0625 Pounds

Ratings for Benzodent (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

FOR DENTAL PAIN: Benzodent provides temporary relief of pain for oral discomfort caused by dentures, braces or sores, with the maximum amount of benzocaine allowed in an over the counter oral product.
LONG LASTING RELIEF: Benzodent is a thick topical cream that provides pain relief with the strength of benzocaine. The unique formula cushions & adheres to gums for pain relief that lasts for hours.
Show More

UlcerEase Anesthetic Mouth Rinse, Bottle, Updated Packaging, 6 Fl Oz

BLUE LIZARD
B01AVFMWYU
2.0 x 2.0 x 5.19 Inches
0.3813 Pounds

Ratings for BLUE LIZARD (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

FAST RELIEF – Ulcer Ease provides fast-acting temporary pain relief for mouth ulcers, canker sores, and other irritations in the mouth and upper throat.
GENTLE ON YOUR MOUTH – Ulcer Ease is pH-balanced to promote oral health. Does not stain teeth.
Show More

Top 10 Oral Pain Treatments - Verified to Buy (Apr. 2024)

Top 10 Oral Pain Treatments Brands on Amazon

Here is the list of top-rated brands that were evaluated by CherryPicks.

  • DenTek
  • Orajel
  • Anbesol
  • Oral-B
  • Benzodent
  • Red Cross
  • S&T INC.
  • GUM
  • IODENT
  • Kanka

Top 10 Oral Pain Treatments Sellers: CPR Seller Rank List

CPR sellers rank is based on CherryPicks-AI bestselling ranking system that helps us analyze each seller's sales trends. The List of top seller ranks is our in-house data, essential for our product ranking to help you make the right shopping choice.

Rank Name Yearly Feedbacks Avg. Ratings
🥇 VerSure 25,732 4.9
🥈 Wiki Deals 16,691 4.9
🥉 LY Berditchev Co. 16,122 4.9
4 Mr. Medical 13,973 4.9
5 SportingDoc 13,665 4.9
6 Royal Meds 11,825 4.8
7 My Great Goods 10,307 4.9
8 RGM GROUP 7,854 4.9
9 Pharmapacks 5,417 4.8
10 PHARMCO 5,243 4.9
View or download top Oral Pain Treatments seller & rating report
VerSure [25732] Wiki Deals [16691] LY Berditchev Co. [16122] Mr. Medical [13973] SportingDoc [13665] Royal Meds [11825] My Great Goods [10307] RGM GROUP [7854] Pharmapacks [5417] PHARMCO [5243] VerSure 20% Wiki Deals 13% LY Berditchev Co. 13% Mr. Medical 11% SportingDoc 11% Royal Meds 9% My Great Goods 8% RGM GROUP 6% Pharmapacks 4% PHARMCO 4%

[Get] Oral Pain Treatments Deals (✅Exclusively for Prime)

What does "Amazon Fulfilled" Mean?

Amazon Fulfilled refers to products handled by Amazon's logistics, which indicates that the product is stored, packed, and shipped by Amazon from one of its fulfillment centers.

When you order a product that is "Amazon Fulfilled," Amazon takes care of the storage, packing, shipping, and customer service for that product. This often ensures quicker delivery and better customer service compared to products that are not fulfilled by Amazon. It also means that the product is eligible for Amazon's return policy.

What does "Prime" Mean?

"Prime" refers to Amazon Prime Member (Join Amazon Prime Now), which indicates eligibility for Prime benefits. When you see "Prime" next to a product on Amazon, This generally means that if you are  an Amazon Prime member, you can get free two-day shipping on that product, and sometimes even same-day or one-day shipping depending on your location.

Prime members also have access to other benefits, including 2-Day ShippingExclusive Member DealsPrime VideoBuy With PrimeAmazon MusicPrime Gaming, and more.

Shop Prime Oral Pain Treatments Deals

What does "Free Shipping" Mean?

"Free Shipping" means that you will not be charged additional fees for the shipping of that product. However, unlike "Prime," which usually guarantees fast two-day shipping, "Free Shipping" doesn't necessarily mean fast shipping.

Sometimes there might be a minimum purchase requirement to qualify for free shipping if you are not a Prime member. For Prime members, the "Free Shipping" usually refers to the free two-day shipping that is one of the benefits of the Prime membership.


Why Should You Trust Us?

Now hundreds and thousands of Health Care, Oral Care supplies are available on Amazon, Picking the right one is not easy, and that may take a lot of your time, Right? and What is the best Oral Pain Treatments to buy for new December 2024?

CherryPicks’s Methodology for Evaluating Oral Pain Treatments

We developed the CherryRatings-AI system to identify and score reviews and the CherryPicks-AI ranking system that uses TensorFlow framework to generate the best list, It will help us evaluate Health Care, Oral Care items that sell on Amazon. The score of items is based on over ten parameters such as analyzing customer review content, product reviewing rating statistics, brand reputation evaluation, comparing product price with features, etc, You can visit How We Rank to learn more in detail.

We collected and analyzed 610 of Oral Pain Treatments reviews based on our selection criteria. It helped us shortlist the top qualified and rated Oral Pain Treatments for Health Care, Oral Care, We found that most customers choose Oral Pain Treatments with an average price of $12.66, and the top brands are Colgate, GUM, Oral-B, Plackers, S&T INC., DenTek, Neosporin, Orajel, BLUE LIZARD, Reazeal, NEOMEN, Anbesol, Benzodent, Red Cross, Gly-Oxide, IODENT, ASRL And Kanka. 

Then our expert-level editors reviewed all those quality items and selected the top 28 Oral Pain Treatments for you, We have researched hundreds of sellers and picked the top sellers for Health Care, Oral Care, including VerSure, Wiki Deals, LY Berditchev Co., Mr. Medical, SportingDoc, Royal Meds, My Great Goods, RGM GROUP, Pharmapacks, PHARMCO, A & H Supply And Bleam. The DenTek Instant Oral Pain Relief Maximum Strengt... are available for purchase right now, and The seller of #1 rank product has received honest feedback from 13,323 consumers with an average rating of 4.5.

We've helped a lot of satisfied users get the right Health & Household product based on their needs, and save lots of time for them to pick Oral Pain Treatments to buy.


Written By Andre M. Willis

You can be my brother if you love groceries because I love them — this were Andre words as at the time of hiring him. He is a great writer, good planner and has got a taste bud that knows what it wants. Keep reading his article to discover the best groceries for healthy eating.